刘春明

姓名

刘春明

性别

女

出生年月

1964.04

职务（职称）

校长，教授

学位

理学博士

E-mail

ccsf777@163.com

办公电话

0431-86168777

办公地址

专业

分析化学

研究方向

天然药物化学

荣誉称号

国务院特殊津贴获得者，吉林省第二批和第三批高级专家，吉林省第四批拔尖创新人才一层次人选，吉林省高等学校教学名师，吉林省第八批有突出贡献的中青年专业技术人才，吉林省优秀专业技术人才。

主讲课程

分析化学，仪器分析，中级化学实验

学习经历

2003.10-2004.10　 澳大利亚Monash大学做高级访问学者

2001.03   -2002.05   中科院长春应用化学研究所博士后

1996.09-2000.06　 吉林大学，化学系，理学博士

1985.09-1988.06　 东北师范大学，化学系，理学硕士

1981.09-1985.06　 东北师范大学，化学系，本科

工作经历

2017.02 -至今　   长春师范大学校长

2007.01-2017.02     长春师范大学副校长

2003.06-2007.01　 长春师范大学教务处处长

2001.01            长春师范大学教授

2000.03-2003.06　 长春师范大学教务处副处长

1996.01            长春师范大学副教授

1991.11-2000.03     长春师范大学化学系教师

1988.07-1991.11　 吉林大学白求恩医学部教师

获奖情况

获吉林省科技进步二等奖3项，三等奖2项，获国家级教学成果二等奖3项，省级教学成果一等奖2项、二等奖1项。近年来代表性获奖如下：

1. 郭飞君，刘春明，闫玉，赵慧君，杨以纲，刘钊，马永双。地方高校培养农村基础教育全科型教师的研究与实践，国家级教学成果二等奖，2014年。

2. 赵骥民，刘益春，刘春明，李元昌，赵志军，于伟，郭飞君。面向农村基础教育培养专家型教师的理论研究与实践探索，国家级教学成果二等奖，2009年。

3. 赵骥民，刘春明，赵慧君，马大风，郭飞君。高师本科科学教育专业的创建与人才培养的研究和实践，国家级教学成果二等奖，2005年。

4. 刘春明，杨以纲，郭飞君，闫玉，赵慧君，刘钊，马永双。地方高校培养农村基础教育全科型教师的研究与实践，吉林省教学成果奖，一等奖，2014年。

5. 刘春明，张语迟，刘舒，郑梅竹，王晶，刘志强，时东方，皮子凤。常用中药材中治疗糖尿病等症的活性成分分离筛选及结构表征研究，吉林省科技进步奖，二等奖，2014年。

6. 刘春明，张语迟，郑梅竹，郭飞君，时东方。传统中药罗布麻抗抑郁有效成分的分离提取及新药开发研究，吉林省科技进步奖，二等奖，2012年。

7. 刘春明，李丽，时东方，皮子凤，郑梅竹，王强，张语迟，王晶。中药苯乙醇苷类化合物提取分离及抗氧化成分活性评价研究，吉林省科技进步奖，二等奖，2010年。

学术成果

专利和学术著作：

申请专利4项，授权专利1项，出版专著及教材5部。代表性成果如下：

1. 刘春明，张语迟，白云鹏，齐艳娟，吴桂梅，一种罗布麻叶提取物的制备方法。专利号：ZL 200910067196.5。

2. 李丽，刘春明. 中药抗氧化成分的现代分离和分析技术，科学出版社，出版时间：2011年5月，ISBN：978-7-03-030933-4

主持科研项目

先后主持国家自然科学基金项目、教育部归国留学人员建设项目、科技厅重点项目、发改委项目、科技厅项目、教育厅项目、横向课题等科研项目30余项，代表性科研项目如下：

1. 国家自然科学基金项目（编号：31670358），药用植物中异黄酮类成分抗缺血性脑卒中的活性筛选及作用机制研究，63万，2017.01-2020.12。

2. 国家自然科学基金项目（编号：31370374），人参属植物抗阿尔茨海默病的活性成分筛选方法及作用机制研究，82万，2014.01-2017.12。

3. 国家自然科学基金项目（编号：31170326），药用植物抗帕金森病的活性成分筛选及作用机制的研究，68万，2012.1-2015.12。

4. 国家自然科学基金项目（编号：30970299），药用植物罗布麻抗抑郁成分的分离、活性评价及作用机制的研究，33万，2010.1-2012.12。

5.吉林省发展和改革委员会项目（编号：2016C077），天然药物分离纯化及活性筛选国家地方联合工程实验室自主创新能力建设，100万，2016.1-2016.12

6. 吉林省科技发展计划项目（编号：20160101336JC），异黄酮类化合物的分离提取及抗癫痫病活性评价研究（探索）：10万，2016.01-2018.12.

7. 教育部归国留学人员实验室建设项目（编号：教财[2011]185号 ），吉林省天然药物分离纯化及活性筛选实验室建设项目，500万，2011.8-2013.8.

8.吉林省科技发展计划项目（编号：20140311032YY），苯乙醇苷类化合物抗衰老保健食品的开发研究，50万2014.1-2016.12.

9. 吉林省科技厅重点项目（编号：20090936），常用中药材中治疗糖尿病等症的活性成分筛选及物质资源库的建立，25万，2011.1-2013.12.  

10. 吉林省科技厅项目（编号：20130521013JH），治疗神经退行性疾病活性成分分离纯化及筛选创新团队，15万，2013.1-2015.12.

11.   吉林省发改委项目（编号：20091041），吉林省中药有效成分分离纯化工程实验室创新能力建设，50万元，2009.12-2010.12.  

12.   吉林省科技厅重点项目（编号：20090936），传统中药罗布麻抗抑郁成分的分离提取及其新药开发研究，29万，2010.6-2012.12.  

13.   吉林省高校重点实验室建设项目（编号：吉教科字[2011]12号），吉林省天然药物分离纯化及活性重点实验室，40万，2011.8-2013.8.

14.   吉林省发改委项目（编号：[2013]779），植物源杀虫成分对天敌昆虫的影响及协调应用技术研究,10万，2013.12-2016.12.

15.   吉林省发改委项目（编号：2009002），植物源生物农药的研究与开发,15万，2010.12-2013.6.  

学术成果

近五年发表的代表性论文

以第一作者或通讯联系人身份在国内外学术期刊上发表论文80余篇，其中有40余篇被SCI检索，近五年来代表性成果如下：

1.   Chunming Liu, Sainan Li, Rong Tsao, Senlin Li, Yuchi Zhang. Extraction   and isolation of potential anti-stroke compounds from black soybean (Glycine   max L. Merrill) guided by in vitro PC12 cell model [J]. Journal of Functional   Foods, 2017, 31, 295–303

2.   Yuchi Zhang, Jianxu Zhang, Chunming Liu*, Min Yu, Sainan Li.   Extraction, isolation, and aromatase inhibitory evaluation of low-polar   ginsenosides from Panax ginseng leaves [J]. Journal of Chromatography A,   2017, 1483, 20–29.

3.   Yuchi Zhang, Jingying Xu, Chunming Liu*, Sainan Li. Screening of   neuraminidase inhibitors from the leaves of Syringa velutina Kom. via   compound fractionation and in vitro activity evaluation [J]. Analytical   Methods, 2017, 9: 500–510.

4.   Senlin Li, Sainan Li, Ying Tang, Chunming Liu*, Lina Chen, Yuchi   Zhang. Ultrafiltration-LC–MS combined with semi-preparative HPLC for the   simultaneous screening and isolation of lactate dehydrogenase inhibitors from   Belamcanda chinensis [J]. Journal of Separation Science, 2016, 39   (23): 4533–4543.

5. Ying Tang, Senlin   Li, Sainan Li, Xiaojing Yang, Yao Qin, Yuchi Zhang, Chunming Liu*.   Screening and isolation of potential lactate dehydrogenase inhibitors from   five Chinese medicinal herbs: Soybean, Radix pueraria, Flos pueraria, Rhizoma   belamcandae, and Radix astragali [J]. Journal of Separation Science,   2016, 39 (11): 2043–2049.

6.   Meizhu Zheng, Chunming Liu*, Yajun Fan,   Dongfang Shi, Yuchi Zhang. Protective Effects of Paeoniflorin   Against MPP+-induced Neurotoxicity in PC12 Cells [J]. Neurochemical Research,   2016, 41 (6): 1323–1334.

7. Yueqi Wang, Ying   Tang, Chunming Liu*, Chong Shi, Yuchi Zhang. Determination and   isolation of potential α-glucosidase and xanthine oxidase inhibitors from   Trifolium pratense L. by ultrafiltration liquid chromatography and high-speed   countercurrent chromatography [J]. Medicinal Chemistry Research, 2016,   25 (5): 1020–1029.

8. Jing Wang, Meizhu   Zheng, Lina Chen, Zhiqiang Liu, Yuchi Zhang, Chun-ming Liu*, Shu Liu.   Rapid screening, separation, and detection of hydroxyl radical scavengers   from total flavonoids of Ginkgo biloba leaves by chromatography combined with   molecular devices [J]. Journal of Separation Science, 2016, 39 (21):   4158–4165

9. Lina Chen, Yao Qin, Xiaojing Yang, Chunming Liu*. Simultaneous determination of seven insecticides   in soft drinks and fruit juices using ultraperformance liquid chromatography   tandem mass spectrometry with product ion confirmation scan mode [J]. Analytical   Methods, 2016, 8: 666–672.

10.   Yao Qin, Lina Chen, Xiaojing Yang, Ying Tang,   Senlin Li, Chunming Liu*. Determination of 19 Representative   Pesticides in Traditional Chinese Medicines by Dispersive Liquid-Liquid   Microextraction and Ultrahigh-Performance Liquid Chromatography–Tandem Mass   Spectrometry [J]. Chromatographia, 2016, 79 (13): 875–884.

学术成果

11.   Yuchi Zhang, Chong Shi, Chunming   Liu*,   Min Yu, Yanjuan Qi, Sainan Li. Saponins from Panax bipinnatifidus Seem.: New   strategy of extraction,isolation, and evaluation of tyrosinase inhibitory   activity based onmathematical calculations [J]. Journal of Chromatography   B, 2016, 1039, 79–87.

12.   Yao Qin, Lina Chen, Xiaojing Yang, Sainan Li, Yumeng Wang, Ying Tang, Chunming Liu*. Multi-residue   method for determination of selected neonicotinoid insecticides in   traditional Chinese medicine using modified dispersive solid-phase extraction   combined with ultra-performance liquid chromatography tandem mass   spectrometry [J]. Analytical Sciences, 2015, 31: 823–830.

13.   Li Li, Bo Li, Huirong Zhang, Anqi Zhao, Binhua Han, Chunming Liu*, Rong Tsao.   Ultrafiltration LC-ESI-MSn screening of MMP-2 inhibitor from selected Chinese   medical herbs Smilax glabra Roxb., Smilax china L. Saponhnikovia   divaricuta(Turcz.) Schischk as potential functional food ingredicens [J]. Journal   of Functional Foods, 2015, 15: 389–395.

14. Bo Li, Li Li, Anqi   Zhao, Binhua Han, Yajun Fan, Chunming Liu*, Jianjun Liu. Preparative   separation of isoflavones in plant extract of Pueraria lobata by high   performance counter-current chromatography [J]. Analytical Methods,   2015, 7: 1321–1327.

15.   Yuchi Zhang, Chunming Liu*, Yanjuan Qi, Sainan Li, Yan Pan, Yuchun Li.   Circulating ultrasound-assisted extraction, countercurrent chromatography,   and liquid chromatography for the simultaneous extraction, isolation, and   analysis of the constituents of Uncaria tomentosa [J]. Journal of   Chromatography A, 2015, 1388: 36–42.

16.   Yuchi Zhang, Chunming Liu*, Jing Li, Yanjuan Qi, Yuchun Li, Sainan Li.   Development of “ultrasound-assisted dynamic extraction” and its combination   with CCC and CPC for simultaneous extraction and isolation of phytochemicals   [J]. Ultrasonics Sonochemistry, 2015, 26: 111–118.

17.   Yuchi Zhang, Chunming Liu*, Yanjuan Qi, Yuchun Li, Sainan Li. Dynamic   ultrasonic-assisted extraction coupled with paralleled counter-current   chromatography for continuous extraction and online isolation of xanthenones   from Garcinia mangostana [J]. Separation and Purification Technology,   2015, 144: 215–222.

18.   Yuchi Zhang, Chunming Liu*, Yan Pan, Yanjuan Qi, Yuchun Li, Sainan Li,   Yueqi Wang. Ultrasound assisted dynamic extraction coupled with parallel   countercurrent chromatography for simultaneous extraction, purification, and   isolation of phytochemicals: Application to isoflavones from red clover [J]. Analytical   and Bioanalytical Chemistry, 2015,   407: 4597–4606.

19.   Yuchi Zhang, Chunming Liu*, Yanjuan Qi, Yuchun Li, Sainan Li.   Development of circulating ultrasound-assisted online extraction coupled to   CCC and CPC for simultaneous extraction and isolation of phytochemicals:   Application to Ligusticum chuanxiong Hort [J]. Industrial &   Engineering Chemistry Research, 2015, 54, 3009−3017.

20.   Sainan Li, Ying Tang, Chunming Liu*, jing Li, Liping Guo, Yuchi Zhang.   Development of a method to screen and isolate potential xanthine oxidase   inhibitors from Panax japlcusvar via ultrafiltration liquid chromatography   combined with counter-current chromatography [J]. Talanta, 2015, 134:   665–673

学术成果

21.   Sainan Li, Ying Tang, Chunming Liu*, Yuchi Zhang. Development of a   method to screen and isolate potential - glucosidase inhibitors from Panax   japonicus C.A. Meyer by ultrafiltration, liquid chromatography, and   counter-current chromatography [J]. Journal of Separation Science, 2015, 38, 2014–2023 (SCI, IF=2.571)

22. Sainan Li, Chunming   Liu*, Liping Guo, Yuchi Zhang, Jing Wang, Bing Ma, Yueqi Wang, Yumeng   Wang, Junqi Ren, Xiaojing Yang, Yao Qin, Ying Tang. Ultrafiltration liquid   chromatography combined with high-speed countercurrent chromatography for   screening and isolating potential α-glucosidase and xanthine oxidase   inhibitors from Cortex Phellodendri [J]. Journal of Separation Science,   2014, 37 (18): 2504–2512.

23.   Yang Hu, Chunming Liu*, Lei Cong, Yuchi Zhang, Yunmei Hu, Sainan Li.   Application of high-performance counter-current chromatography and   medium-pressure liquid chromatography for rapid isolation of lactones from   Ligusticum Chuanxiong Hort.   Journal of Liquid Chromatography & Related Technologies, 2014,   37:1187–1198.

24.   Jing Wang, Shu Liu, Bing Ma, Lina Chen, Fengrui Song, Zhiqiang Liu, Chun-ming   Liu*. Rapid screening and detection of XOD inhibitors from S. tamariscina   by ultrafiltration LC-PDA–ESI-MS combined with HPCCC [J]. Analytical and   Bioanalytical Chemistry, 2014, 406: 7379–7387

25.   Jing Wang, Shu Liu, Sainan Li, Fengrui Song, Yuchi Zhang, Zhiqiang Liu, Chun-ming   Liu*. Ultrafiltration LC-PDA-ESI/MS combined with reverse phase-medium   pressure liquid chromatography for screening and isolation potential   a-glucosidase inhibitors from Scutellaria baicalensis Georgi [J]. Analytical   Methods, 2014, 6, 5918–5924.

26. Sainan Li, Liping   Guo, Chunming Liu*, Yuchi Zhang. Application of supercritical fluid   extraction coupled with counter–current chromatography for extraction and   online isolation of unstable chemical components from Rosa   damascena. Journal of Separation Science, 2013, 36 (13):   2104–2113.

27.   Sainan Li, Liping Guo, Chunming Liu*, Zi′ao Fu, Yuchi Zhang.   Combination of supercritical fluid extraction with counter-current   chromatography to isolate anthocyanidins from the petals of Chaenomeles   sinensis based on mathematical calculations. Journal of Separation Science,   2013, 36 (21–22): 3517–3526.

28.   Meizhu Zheng, Yajun Fan, Dongfang Shi, Chunming Liu*.   Antidepressant-like effect of flavonoids extracted from Apocynum venetum   leaves on brain monoamine levels and dopaminergic system [J]. Journal of   Ethnopharmacology, 2013, 147: 108–113.

29.   Yuchi Zhang, Liping Guo, Chunming Liu*, Zoao Fu, Lei Cong, Yanjuan Qi,   Dongping Li, Sainan Li. Wang Jing. Pressurized liquid extraction coupled with   countercurrent chromatography for systematic isolation of chemical   constituents by preprogrammed automatic control [J]. Journal of   Chromatography B, 2013, 935: 16–25.

30.   Yuchi Zhang, Chunmin Liu*, Yanjuan Qi, Sainan Li, Jing Wang.   Application of accelerated solvent extraction coupled with counter-current   chromatography to extraction and online isolation of saponins with a broad   range of polarity from Panax notoginseng [J]. Separation and   Purification Technology, 2013, 106: 82–89.